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Critical Values

Haematology
Sr. No. Parameter Units Biological Ref Interval Critical Range
1 Haemoglobin G% M: 13-18 gm%, F: 11.5-16 gm% < 5 , > 20
2 HCT / PCV % 35.0 – 50.0 % -
3 Total Leucocyte count /c mm 4000-10000 <1000, >50000
4 Differential Count %
c mm
Polymorphs 40-70%
Absolute 1200 – 6800/c mm
Eosinophils 1-6 %
Absolute 40 – 240/c mm
Basophils
Absolute 0 – 40/c mm
Lymphocytes 17-48.0 %
Absolute 1200 -3200/c mm
Monocyte 4.0 – 10.0 %
Absolute 160-400/c mm
Immature cells present
5 Platelet Count /cu.mm 150000-450000 < 50000
6 RBC /cu.mm 150000-450000 > 1,20,000
7 MCV µm3 80 - 97 -
8 MCH pg 26.5 – 33.5 -
9 MCHC g/dl 31.5 – 36.5 -
10 RDW % 10.0 – 15.0 -
11 MPV µm3 6.5 – 11.0 -
12 PDW % 10.0 – 18.0 -
13 Bleeding Time minutes 1 – 5 min >10 minutes
14 Clotting time minutes 4 – 10 min >13 minutes
Clinical Pathology
Sr. No. Parameter Units Reference  Interval Critical  Range
1 Stool Examination     Positive for occult blood, C. vibrio
2 Urine     Sugar +++ +, Protein ++++
3 Sputum ZN staining     AFB positive
ELISA
Sr. No. Parameter Units Reference  Interval Critical  Range
1 HIV/HBs Ag   Negative Positive*
To be informed only to clinician i/c.
2 TORCH (IgG )      
  TOXOPLASMA IU / ml LESS THAN 10 IU / ml = NEGATIVE
MORE THAN 10 IU / ml = POSITIVE
 
  RUBELLA IU / ml LESS THAN 10 IU / ml = NEGATIVE
MORE THAN 10 IU / ml = POSITIVE
 
  CMV IU / ml LESS THAN 0.5 IU / ml = NEGATIVE
MORE THAN 0.5 IU / ml = POSITIVE
 
  HSV I AND II AU / ml LESS THAN 5 AU / ml = NEGATIVE
MORE THAN 5 AU / ml = POSITIVE
 
3 TORCH (IgG )      
  TOXOPLASMA IU / ml LESS THAN 0.5 = NEGATIVE
MORE THAN 0.5 = POSITIVE
 
  RUBELLA IU / ml LESS THAN 0.6 = NEGATIVE
MORE THAN 0.8 = POSITIVE
 
  CMV IU / ml LESS THAN 0.4 = NEGATIVE
MORE THAN 0.5 = POSITIVE
 
  HSV I AND II AU / ml LESS THAN 0.5 = NEGATIVE
MORE THAN 0.5 = POSITIVE
 
4 TB (IgG) U/L LESS THAN 125 = NEGATIVE
MORE THAN 25 = POSITIVE
 
5 TB (IgG)   LESS THAN 1.0 = NEGATIVE
0.8 – 1.0 = EQUIVOCAL
MORE THAN 1.0 = POSITIVE
 
BIOCHEMISTRY
Sr. No. Parameter Units Biological Ref Interval Critical Range
1 Glucose mg/dl FBS: 70-110, 
PMBS: 110-160
Fasting blood sugar: >250 mg/dl
Post meal blood sugar: >300 mg/dl
Random blood sugar: >250 mg/dl
2 Blood Urea mg/dl 25-40 >90 mg%
3 S. Creatinine mg/dl 0-1.5 >3 mg%
4 S. Sodium m eq/L 135-145 <120, >160  m eq/L
5 S. Potassium m eq/L 3.6-5.0 <2.0, >6.0 m eq/L
6 S. Chloride
m eq/L 98-119 <85 m eq/L
7 Ionic Calcium m mol/L 1.1 – 1.4 m mol/L <0.6, >1.6 m mol/L
8 Total Bilirubin mg/dl 0-1.2 >10 mg%
9 Direct Bilirubin mg/dl 0-0.2 >10 mg/dl
10 Indirect Bilirubin mg/dl 0.1-1.1 -
11 Total Protein mg/dl 6-8 <3 G/dl
12 Sr. Albumin G /dl 3.5-5.5 <1.5 G/dl
13 Sr. Globulin G /dl 2.5- 3.5 <1.0 G/dl
14 Sr. SGOT/AST G /dl 8-40 >1000 U/L
15 Sr. SGPT/ALT U/L 8-40 >1000 U/L
16 Sr. Alkaline Phosphatase U/L 108-306 >800 U/L
17 Total  Calcium mg/dl 8.5-10.5 <7.0 mg/dl
18 Uric Acid mg/dl Male: 3.5-7.2
Female: 2.6-6.0
>15 mg/dl
19 CK NAC U/L Male:  <171
Female: <145
>500 U/L
20 CK MB U/L Up to 25 >40 U/L
21 S. Cholesterol mg/dl Desirable Chol: <200
Border line:200-220
High chol:>220
>400 mg/dl
22 HDL mg/dl 30-70 <10 mg/dl
23 S. Triglycerides mg/dl Normal:<150 
Border line:150-200
High :200-500
Very high:>500
>600 mg/dl
24 Amylase mg/dl Up to 85 >700 mg/dl
25 Lipase u/L Up to  200 u/L >700 mg/dl
26 HbA1C gm% Non diabetic – 4.4 – 6.7 gm%
Goal – 6.7 – 7.3
Good control – 7.3 – 9.1
Action suggested  > 9.1 gm%
 
27 Iron u mol/L 10.7-28.6 u mol/L  
28 TIBC u mol/L 44.7 – 71.6 u mol/L  
29 LDH u/L 102 – 227 u/L  
30 Lactate m/mol/L 0.5 – 2.2 m mol/L  
31 Cholinesterase u/L 4900 -11900 u/L  
32 G6PD u/gHb 4.6- 13.5 u/g Hb  
33 PO4 mg/dl 2.5 – 5.0 mg/dl  
34 D - Dimer ng/ml <200 ( Negative)  
35 RA u/L Up to 30 u/L  
36 ASO IU/ml Up to 200  
37 ADA u/L 30 -40 Suspected
40 – 60 strong suspected
More than 60 +
 
Hepatitis Markers
Sr. No. Parameter Units Biological Ref Interval Critical Range
1 HAV IgM   < 0.80 (Non-reactive)
0.80-1.20 (Gray zone) > 1.20 (Reactive)
 
2 HBsAg IU/ml < 0.05 IU/ml (Non-reactive)
> 0.05 IU/ml (Reactive)
 
3 Hep. B env. Ag   < 1.00 (Non-reactive)
> 1.00 (Reactive)
 
4 Anti HBe   > 1.00 (Non-reactive)
< 1.00 (Reactive)
 
5 Hep. B core IgM   < 1.00 (Non-reactive)
> 1.00 (Reactive)
 
6 Hep. B core Total   < 1.00 (Non-reactive)
> 1.00 (Reactive)
 
7 Anti HCV   Upto 0.9 (Non reactive)
0.9 – 1.0 (Gray zone)
More than 1.0 (Reactive)
-
In-Fertility Hormones
Sr. No. Parameter Units Biological Ref Interval Critical Range
1 FSH mIU/ml Men: 0.95-11.95 mIU/ml
Women:
Follicular Phase : 3.03-8.08 mIU/ml
Mid-cycle peak : 2.55 -16.69 mIU/ml
Luteal Phase : 1.38-5.47 mIU/ml
Post – menopausal females: 26.72 – 133.41 mIU/ml
 
2 LH mIU/ml Males: 1.14-8.75 mIU/ml
Follicular Phase: 2.39-6.60 mIU/ml
Mid – cycle Peak: 9.05 -74.24 mIU/ml
Luteal Phase: 0.90-9.33 mIU/ml
Post – menopausal females: 10.39-64.57 mIU/ml
 
3 Prolactin ng/ml Males: 3.46 – 19.40 ng/ml
Females: 5.18 – 26.53 ng/ml
 
4 B HCG mlU/ml < 5.00 mlU/ml – Negative
5-25 mlU/ml – Early Pregnancy
> 25 mlU/ml – Positive
Weeks post LMP ( Last Menstrual Period)
1-10 weeks : 201.64 - > 225000.00
11-15 weeks: 22.536.49 – >225000.00
16-22 weeks : 8006.62 – 50238.60
23 – 40 weeks : 1599.80 – 49412.65
 
5 DHE AS µg/dl Females:
11-14 yrs: 8.6 – 169.8 µg/dl
15 – 19 yrs: 61.2 – 493.6 µg/dl
20- 24 yrs : 134.2 – 407 .4 µg/dl
25 – 34 yrs: 95.8 – 511.7 µg/dl
35- 44 yrs: 74 .8 – 410.2 µg/dl
45 -54 yrs: 56.2 – 282.9 µg/dl
55 – 64 yrs: 29.7 – 182.2 µg/dl
65-70 yrs: 33.6 – 78.9 µg/dl

Males:
11-14 yrs: 16.6 – 242.7 µg/dl
15 – 19 yrs: 45.1 – 385.0 µg/dl
20- 24 yrs : 238.4 – 539.3 µg/dl
25 – 34 yrs: 167.9 – 591.9 µg/dl
35- 44 yrs: 139.7 – 484.4 µg/dl
45 -54 yrs: 136.2 – 447.6 µg/dl
55 – 64 yrs: 48.6 – 361.8 µg/dl
65-70 yrs: 228.5 – 283.6 µg/dl

Children:
< 1week:24.6 – 302.8 µg/dl
1-4 weeks:8.5 – 317.3 µg/dl
1-12 months: 31.6 – 214.1 µg/dl
1 – 4 yrs:32.7 – 276.0 µg/dl
5 – 10yrs:24.4 – 209.7 µg/dl
 
6 Testosterone ng/ml Males: 1.56-8.77 ng/ml
Females: 0.09-1.30 ng/ml
 
Thyroid Hormones
Sr. No. Parameter Units Biological Ref Interval Critical Range
1 Total T3 ng/ml 58 – 159 ng/ml  
2 Total T4 µg/dl 4.87 – 11.72 µg/dl  
3 TSH µIU/ml 0.35 - 4.94 µIU/ml  
4 Free T4 ng/dl 0.70  - 1.48 ng/dl  
5 Free T3 pg/ml 1.71 - 3.71 pg/ml  
Thyroid Hormones
Sr. No. Parameter Units Biological Ref Interval Critical Range
1 Total PSA ng/ml Less than 4.0 ng/ml  
2 Free PSA ng/ml 0.5 -2.5 ng/ml -
3 AFP ng/ml 1.09 – 8.04 ng/ml

Gestation week: (Serum)
15 : 71.1 – 106.6 ng/ml
16 : 80.6 – 120.9 ng/ml
17: 91.4 – 137.2 ng/ml
18: 103.7 – 155.6 ng/ml
19: 117.7 – 176.5 ng/ml
20: 133.5 – 200.2 ng/l
21: 151.4 – 227.1 ng/ml

Gestation week: (Amniotic fluid)
15 : 37.5 – 56.2 µg/dl
16 : 31.3 – 47.0 µg/dl
17: 26.1 – 39.2 µg/dl
18: 21.8 – 32.8 µg/dl
19: 18.2 – 27.4 µg/dl
20: 15.2 – 22.9 µg/dl
21: 12.7 – 19.1 µg/dl
 
4 CA 15      
5 CA 19.9 U/ml 0 - 37.0 U/ml  
6 CA 125 U/ml 0 – 35.0 U/ml  
Others
Sr. No. Parameter Units Biological Ref Interval Critical Range
1 Troponin I ng/ml 0.0 – 0.3 ng/ml  
2 Homocysteine µmol/L Male: 5.46 µmol/L – 16.20 µmol/L
Female: 4.44 µmol/L – 13.56 µmol/L
(Overall: 5.085.46 µmol/L – 15.39 µmol/L
 
3 FERRITIN ng/ml Male : 21.81 – 274.66 ng/ml
Females : 4.63 – 204.00 ng/ml
 
4 BNP pg/ml 0-100 pg/ml  
5 Vitamin B12 pg/ml 187-883 pg/ml (138-652 pmol/L)  
6 HIV Ag/Ab   Upto 0.9 (Non-reactive)
0.9 – 1.0 (Gray zone)
More than 1.0 (Reactive)
 
7 Testosterone ng/ml Males: 1.56-8.77 ng/ml
Females: 0.09-1.30 ng/ml
 
8 Vitamin D3 ng /ml 11.1 – 42.9 ng /ml  
9 S. Cortisol µg/dl Before 10 am: 3.7 – 19.4 µg/dl
After 5 pm: 2.9 – 17.3 µg/dl
 
10 Anti CCP u/ml 0.0 – 5.0 u/ml -
11 Parathyroid H pg/ml 15.0 – 68.3 pg/ml -